You may report side effects to FDA at 1-800-FDA-1088.

Avoid using other medicines that make you sleepy. Ativan can cause side effects that may impair your thinking or reactions. 2-amino-2′,5-dichlorobenzophenone is reacted with hydroxylamine. S. On regular administration diazepam will, however, accumulate more, since it has a longer half-life and active metabolites with even longer half-lives. Lorazepam is considered to be a short-acting drug which, similar to other benzodiazepines, exerts its therapeutic as well as adverse effects via its interaction at benzodiazepine binding sites, which are located on GABAA receptors in the central nervous system. Do not use Ativan without your doctor's consent if you are pregnant. The intermediate oxime is then reacted with chloracetyl chloride, and upon heterocyclization 6-chloro-2-chlormethyl-4-(2′-chlorophenyl)quinazolin-3-oxide is formed. The elderly metabolise benzodiazepines more slowly than younger people and are more sensitive to the adverse effects of benzodiazepines compared to younger individuals even at similar plasma levels. Lorazepam is high-potency and an intermediate-acting benzodiazepine and its uniqueness, advantages and disadvantages are largely explained by its pharmacokinetic properties (poor water and lipid solubility, high protein binding and non-oxidative metabolism to a pharmacologically inactive glucuronide form) and by its high relative potency (lorazepam 1 mg is equal in effect to diazepam 10 mg).